Adams & Graham's Introduction to Neuropathology, Edition: by David I. Graham, James A.R. Nicoll, Ian Bone (Eds.)

By David I. Graham, James A.R. Nicoll, Ian Bone (Eds.)

Creation to Neuropathology 3Ed is still an introductory textual content, yet extra scientific fabric has been brought to make it proper to neurologists and a few psychiatrists, in addition to pathologists. This comprises the addition of small quantities of textual content all through, plus neuroimages, together with practical MRI, that is in color. furthermore, the textual content has been up to date all through with a brand new workforce of contributing authors.

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Additional info for Adams & Graham's Introduction to Neuropathology, Edition: 3rd

Sample text

Bilateral parietal lobe disease is rare, though it can occur as the result of a hypotensive episode with bilateral arterial boundary zones ischemia. Unilateral disease is most frequently due to middle cerebral artery territory ischemic cerebrovascular disease (Fig. 16), usually large-vessel thromboembolic occlusive disease from the heart, aortic arch or carotid system. Lobar hematomas may present in the parietal region (amyloid angiopathy) as may pyogenic or fungal infection, primary and metastatic tumors.

This representation ensures that refined and sophisticated movements are better served whilst cruder movements such as at a large joint require only a small area of cortex to execute (Hughlings Jackson’s ‘hierarchical’ theory once more). Damage to the motor cortex results in contralateral hemiplegia. If the medial cortex is affected primarily, as in occlusion of the anterior cerebral artery or by compression from a parasagittal tumor, paralysis is evident in the leg, with sparing of the trunk, upper limb and face.

9). These layers are not of homogeneous thickness throughout the cerebral cortex, but show considerable regional variation; for example, in that part of the neocortex that receives major sensory projections, the granular layer is more prominent than the pyramidal layer (granular cortex), the opposite being the case in areas from which major motor projections emanate (the agranular or pyramidal cortex). Based on these subtle differences in cytoarchitecture, Brodmann (1909) and Von Economo (1927) divided the cerebral cortex into specific regions, implying that each discrete area had a specific and unique function.

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